2p7f

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[[Image:2p7f.png|left|200px]]
[[Image:2p7f.png|left|200px]]
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==About this Structure==
==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7F OCA].
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[[2p7f]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P7F OCA].
==Reference==
==Reference==
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A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization., Torelli AT, Krucinska J, Wedekind JE, RNA. 2007 Jul;13(7):1052-70. Epub 2007 May 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17488874 17488874]
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<ref group="xtra">PMID:17488874</ref><ref group="xtra">PMID:16411744</ref><ref group="xtra">PMID:16262240</ref><references group="xtra"/>
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Water in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transfer., Salter J, Krucinska J, Alam S, Grum-Tokars V, Wedekind JE, Biochemistry. 2006 Jan 24;45(3):686-700. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16411744 16411744]
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Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn., Alam S, Grum-Tokars V, Krucinska J, Kundracik ML, Wedekind JE, Biochemistry. 2005 Nov 8;44(44):14396-408. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16262240 16262240]
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[[Category: Krucinska, J.]]
[[Category: Krucinska, J.]]
[[Category: Torelli, A T.]]
[[Category: Torelli, A T.]]
[[Category: Wedekind, J E.]]
[[Category: Wedekind, J E.]]
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[[Category: 2',5' phosphodiester]]
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[[Category: 2s']]
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[[Category: 5' phosphodiester]]
[[Category: Active site water]]
[[Category: Active site water]]
[[Category: Hairpin ribozyme]]
[[Category: Hairpin ribozyme]]
[[Category: Induced fit]]
[[Category: Induced fit]]
[[Category: Reaction intermediate]]
[[Category: Reaction intermediate]]
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[[Category: Rna]]
[[Category: Transition-state stabilization]]
[[Category: Transition-state stabilization]]
[[Category: Vanadate]]
[[Category: Vanadate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:09:39 2008''
 

Revision as of 18:22, 14 March 2011

Image:2p7f.png

Template:STRUCTURE 2p7f

The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme

Template:ABSTRACT PUBMED 17488874

About this Structure

2p7f is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Torelli AT, Krucinska J, Wedekind JE. A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization. RNA. 2007 Jul;13(7):1052-70. Epub 2007 May 8. PMID:17488874 doi:rna.510807
  • Salter J, Krucinska J, Alam S, Grum-Tokars V, Wedekind JE. Water in the active site of an all-RNA hairpin ribozyme and effects of Gua8 base variants on the geometry of phosphoryl transfer. Biochemistry. 2006 Jan 24;45(3):686-700. PMID:16411744 doi:10.1021/bi051887k
  • Alam S, Grum-Tokars V, Krucinska J, Kundracik ML, Wedekind JE. Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn. Biochemistry. 2005 Nov 8;44(44):14396-408. PMID:16262240 doi:10.1021/bi051550i

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