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1nwl

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==Disease==
==Disease==
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Known disease associated with this structure: Abdominal body fat distribution, modifier of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]], Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]]
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Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]]
==About this Structure==
==About this Structure==
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1NWL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWL OCA].
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1NWL is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWL OCA].
==Reference==
==Reference==
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Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering., Erlanson DA, McDowell RS, He MM, Randal M, Simmons RL, Kung J, Waight A, Hansen SK, J Am Chem Soc. 2003 May 14;125(19):5602-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12733877 12733877]
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<ref group="xtra">PMID:12733877</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Single protein]]
 
[[Category: Erlanson, D A.]]
[[Category: Erlanson, D A.]]
[[Category: Hansen, S.]]
[[Category: Hansen, S.]]
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[[Category: Protein-small molecule inhibitor complex]]
[[Category: Protein-small molecule inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:38:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:17:24 2009''

Revision as of 22:17, 17 February 2009

Template:STRUCTURE 1nwl

Contents

Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic

Template:ABSTRACT PUBMED 12733877

Disease

Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[176885]

About this Structure

1NWL is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Erlanson DA, McDowell RS, He MM, Randal M, Simmons RL, Kung J, Waight A, Hansen SK. Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering. J Am Chem Soc. 2003 May 14;125(19):5602-3. PMID:12733877 doi:10.1021/ja034440c

Page seeded by OCA on Wed Feb 18 00:17:24 2009

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