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2rfn
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2RFN is a | + | 2RFN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFN OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:18055465</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Bellon, S F.]] | [[Category: Bellon, S F.]] | ||
[[Category: Dussault, I.]] | [[Category: Dussault, I.]] | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 01:58:26 2009'' |
Revision as of 23:58, 17 February 2009
Contents |
x-ray structure of c-Met with inhibitor.
Template:ABSTRACT PUBMED 18055465
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
2RFN is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bellon SF, Kaplan-Lefko P, Yang Y, Zhang Y, Moriguchi J, Rex K, Johnson CW, Rose PE, Long AM, O'Connor AB, Gu Y, Coxon A, Kim TS, Tasker A, Burgess TL, Dussault I. c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations. J Biol Chem. 2008 Feb 1;283(5):2675-83. Epub 2007 Nov 30. PMID:18055465 doi:10.1074/jbc.M705774200
Page seeded by OCA on Wed Feb 18 01:58:26 2009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Bellon, S F. | Dussault, I. | Kaplan-Lefko, P. | Moriguchi, J. | Yang, Y. | Zhang, Y. | Atp-binding | C-met hgf receptor tyrosine kinse kinase domain | Glycoprotein | Membrane | Nucleotide-binding | Phosphorylation | Proto-oncogene | Transferase | Transmembrane | Tyrosine-protein kinase
