1odk
From Proteopedia
(New page: 200px<br /> <applet load="1odk" size="450" color="white" frame="true" align="right" spinBox="true" caption="1odk, resolution 1.90Å" /> '''PURINE NUCLEOSIDE P...) |
|||
Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
- | 1ODK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]] with GOL as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.28 2.4.2.28]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ODK OCA]]. | + | 1ODK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]] with GOL as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/S-methyl-5-thioadenosine_phosphorylase S-methyl-5-thioadenosine phosphorylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.28 2.4.2.28]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ODK OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus., Tahirov TH, Inagaki E, Ohshima N, Kitao T, Kuroishi C, Ukita Y, Takio K, Kobayashi M, Kuramitsu S, Yokoyama S, Miyano M, J Mol Biol. 2004 Apr 9;337(5):1149-60. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15046984 15046984] | Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus., Tahirov TH, Inagaki E, Ohshima N, Kitao T, Kuroishi C, Ukita Y, Takio K, Kobayashi M, Kuramitsu S, Yokoyama S, Miyano M, J Mol Biol. 2004 Apr 9;337(5):1149-60. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15046984 15046984] | ||
+ | [[Category: S-methyl-5-thioadenosine phosphorylase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
Line 26: | Line 27: | ||
[[Category: transferase]] | [[Category: transferase]] | ||
- | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:35:34 2007'' |
Revision as of 11:30, 30 October 2007
|
PURINE NUCLEOSIDE PHOSPHORYLASE FROM THERMUS THERMOPHILUS
Overview
The purine nucleoside phosphorylase from Thermus thermophilus crystallized, in space group P4(3)2(1)2 with the unit cell dimensions a = 131.9 A and c, = 169.9 A and one biologically active hexamer in the asymmetric unit. The, structure was solved by the molecular replacement method and refined at a, 1.9A resolution to an r(free) value of 20.8%. The crystals of the binary, complex with sulfate ion and ternary complexes with sulfate and adenosine, or guanosine were also prepared and their crystal structures were refined, at 2.1A, 2.4A and 2.4A, respectively. The overall structure of the, T.thermophilus enzyme is similar to the structures of hexameric enzymes, from Escherichia coli and Sulfolobus solfataricus, but significant, differences are observed in the purine base recognition site. A ... [(full description)]
About this Structure
1ODK is a [Single protein] structure of sequence from [Thermus thermophilus] with GOL as [ligand]. Active as [S-methyl-5-thioadenosine phosphorylase], with EC number [2.4.2.28]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus., Tahirov TH, Inagaki E, Ohshima N, Kitao T, Kuroishi C, Ukita Y, Takio K, Kobayashi M, Kuramitsu S, Yokoyama S, Miyano M, J Mol Biol. 2004 Apr 9;337(5):1149-60. PMID:15046984
Page seeded by OCA on Tue Oct 30 13:35:34 2007
Categories: S-methyl-5-thioadenosine phosphorylase | Single protein | Thermus thermophilus | Inagaki, E. | Miyano, M. | RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative. | Tahirov, T.H. | GOL | Alpha-beta protein | Nucleoside phosphorylase | Riken structural genomics/proteomics initiative | Rsgi | Structural genomics | Transferase