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2ipj

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==About this Structure==
==About this Structure==
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2IPJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPJ OCA].
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2IPJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPJ OCA].
==Reference==
==Reference==
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Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding., Faucher F, Cantin L, Pereira de Jesus-Tran K, Lemieux M, Luu-The V, Labrie F, Breton R, J Mol Biol. 2007 Jun 1;369(2):525-40. Epub 2007 Mar 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17442338 17442338]
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<ref group="xtra">PMID:17442338</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Breton, R.]]
[[Category: Breton, R.]]
[[Category: Cantin, L]]
[[Category: Cantin, L]]
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[[Category: Open conformation]]
[[Category: Open conformation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:05:13 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:39:42 2009''

Revision as of 05:39, 18 February 2009

Template:STRUCTURE 2ipj

Contents

Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant Y24A in complex with NADP+ and epi-testosterone

Template:ABSTRACT PUBMED 17442338

Disease

Known disease associated with this structure: Obesity, hyperphagia, and developmental delay OMIM:[600450]

About this Structure

2IPJ is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Faucher F, Cantin L, Pereira de Jesus-Tran K, Lemieux M, Luu-The V, Labrie F, Breton R. Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding. J Mol Biol. 2007 Jun 1;369(2):525-40. Epub 2007 Mar 27. PMID:17442338 doi:10.1016/j.jmb.2007.03.058

Page seeded by OCA on Wed Feb 18 07:39:42 2009

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