2rgu
From Proteopedia
(Difference between revisions)
| Line 20: | Line 20: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2RGU is a | + | 2RGU is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGU OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:18052023</ref><references group="xtra"/> | |
[[Category: Dipeptidyl-peptidase IV]] | [[Category: Dipeptidyl-peptidase IV]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Eckhardt, M.]] | [[Category: Eckhardt, M.]] | ||
[[Category: Himmelsbach, F.]] | [[Category: Himmelsbach, F.]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:54:56 2009'' |
Revision as of 06:54, 18 February 2009
Crystal structure of complex of human DPP4 and inhibitor
Template:ABSTRACT PUBMED 18052023
About this Structure
2RGU is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Eckhardt M, Langkopf E, Mark M, Tadayyon M, Thomas L, Nar H, Pfrengle W, Guth B, Lotz R, Sieger P, Fuchs H, Himmelsbach F. 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin -2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. J Med Chem. 2007 Dec 27;50(26):6450-3. Epub 2007 Dec 1. PMID:18052023 doi:10.1021/jm701280z
Page seeded by OCA on Wed Feb 18 08:54:56 2009
