2fx8

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==About this Structure==
==About this Structure==
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2FX8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FX8 OCA].
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2FX8 is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FX8 OCA].
==Reference==
==Reference==
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Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10., Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA, J Mol Biol. 2007 Feb 2;365(5):1533-44. Epub 2006 Nov 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17125793 17125793]
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<ref group="xtra">PMID:17125793</ref><ref group="xtra">PMID:15723805</ref><references group="xtra"/>
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Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41., Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA, Immunity. 2005 Feb;22(2):163-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15723805 15723805]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Brunel, F M.]]
[[Category: Brunel, F M.]]
[[Category: Burton, D R.]]
[[Category: Burton, D R.]]
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[[Category: Immunoglobulin fold]]
[[Category: Immunoglobulin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:09:23 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:49:13 2009''

Revision as of 07:49, 18 February 2009

Image:2fx8.png

Template:STRUCTURE 2fx8

Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with an aib-induced peptide encompassing the 4e10 epitope on gp41

Template:ABSTRACT PUBMED 17125793

About this Structure

2FX8 is a 12 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. J Mol Biol. 2007 Feb 2;365(5):1533-44. Epub 2006 Nov 10. PMID:17125793 doi:10.1016/j.jmb.2006.10.088
  • Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity. 2005 Feb;22(2):163-73. PMID:15723805 doi:10.1016/j.immuni.2004.12.011

Page seeded by OCA on Wed Feb 18 09:49:13 2009

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