2hog
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 2HOG is a | + | 2HOG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HOG OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:16978863</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
- | [[Category: Single protein]] | ||
[[Category: Ikuta, M.]] | [[Category: Ikuta, M.]] | ||
[[Category: Yan, Y.]] | [[Category: Yan, Y.]] | ||
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[[Category: Kinase]] | [[Category: Kinase]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:54:08 2009'' |
Revision as of 07:54, 18 February 2009
crystal structure of Chek1 in complex with inhibitor 20
Template:ABSTRACT PUBMED 16978863
About this Structure
2HOG is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fraley ME, Steen JT, Brnardic EJ, Arrington KL, Spencer KL, Hanney BA, Kim Y, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W, Beck SC, Mao X, Lobell RB, Sepp-Lorenzino L, Yan Y, Ikuta M, Munshi SK, Kuo LC, Kreatsoulas C. 3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6049-53. Epub 2006 Sep 15. PMID:16978863 doi:10.1016/j.bmcl.2006.08.118
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