3bg3

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==Disease==
==Disease==
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Known disease associated with this structure: Pyruvate carboxylase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608786 608786]]
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Known disease associated with this structure: Pyruvate carboxylase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608786 608786]], Thrombophilia due to protein C deficiency, autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612283 612283]], Thrombophilia due to protein C deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612283 612283]]
==About this Structure==
==About this Structure==
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3BG3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BG3 OCA].
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3BG3 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BG3 OCA].
==Reference==
==Reference==
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Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction., Xiang S, Tong L, Nat Struct Mol Biol. 2008 Mar;15(3):295-302. Epub 2008 Feb 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18297087 18297087]
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<ref group="xtra">PMID:18297087</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Pyruvate carboxylase]]
[[Category: Pyruvate carboxylase]]
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[[Category: Single protein]]
 
[[Category: Tong, L.]]
[[Category: Tong, L.]]
[[Category: Xiang, S.]]
[[Category: Xiang, S.]]
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[[Category: Transit peptide]]
[[Category: Transit peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:38:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 10:12:32 2009''

Revision as of 08:12, 18 February 2009

Template:STRUCTURE 3bg3

Contents

Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus)

Template:ABSTRACT PUBMED 18297087

Disease

Known disease associated with this structure: Pyruvate carboxylase deficiency OMIM:[608786], Thrombophilia due to protein C deficiency, autosomal dominant OMIM:[612283], Thrombophilia due to protein C deficiency, autosomal recessive OMIM:[612283]

About this Structure

3BG3 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Xiang S, Tong L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat Struct Mol Biol. 2008 Mar;15(3):295-302. Epub 2008 Feb 24. PMID:18297087 doi:10.1038/nsmb.1393

Page seeded by OCA on Wed Feb 18 10:12:32 2009

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