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3e8r

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(New page: '''Unreleased structure''' The entry 3e8r is ON HOLD Authors: Orth, P. Description: Crystal structure of catalytic domain of TACE with hydroxamate inhibitor ''Page seeded by [http://o...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3e8r.jpg|left|200px]]
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The entry 3e8r is ON HOLD
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{{STRUCTURE_3e8r| PDB=3e8r | SCENE= }}
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Authors: Orth, P.
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===Crystal structure of catalytic domain of TACE with hydroxamate inhibitor===
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Description: Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:01:34 2008''
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{{ABSTRACT_PUBMED_18835710}}
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==About this Structure==
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3E8R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8R OCA].
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==Reference==
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Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: Optimization of the S3' pocket., Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X, Bioorg Med Chem Lett. 2008 Sep 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18835710 18835710]
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[[Category: ADAM 17 endopeptidase]]
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[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Orth, P.]]
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[[Category: Alternative splicing]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Metalloprotease]]
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[[Category: Notch signaling pathway]]
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[[Category: Phosphoprotein]]
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[[Category: Protease]]
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[[Category: Sh3-binding]]
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[[Category: Tace adam17 zn-endopeptidase]]
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[[Category: Transmembrane]]
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[[Category: Zinc]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 22 10:51:38 2008''

Revision as of 08:51, 22 October 2008

Template:STRUCTURE 3e8r

Crystal structure of catalytic domain of TACE with hydroxamate inhibitor

Template:ABSTRACT PUBMED 18835710

About this Structure

3E8R is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: Optimization of the S3' pocket., Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X, Bioorg Med Chem Lett. 2008 Sep 13. PMID:18835710

Page seeded by OCA on Wed Oct 22 10:51:38 2008

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