2r2m

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==About this Structure==
==About this Structure==
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2R2M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2M OCA].
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2R2M is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2M OCA].
==Reference==
==Reference==
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2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17889527 17889527]
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<ref group="xtra">PMID:17889527</ref><references group="xtra"/>
[[Category: Hirudo medicinalis]]
[[Category: Hirudo medicinalis]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Spurlino, J.]]
[[Category: Spurlino, J.]]
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[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:08:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:32:29 2009''

Revision as of 11:32, 17 February 2009

Image:2r2m.png

Template:STRUCTURE 2r2m

Contents

2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors

Template:ABSTRACT PUBMED 17889527

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

2R2M is a 3 chains structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T. 2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527 doi:10.1016/j.bmcl.2007.09.013

Page seeded by OCA on Tue Feb 17 13:32:29 2009

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