1row
From Proteopedia
(New page: 200px<br /><applet load="1row" size="450" color="white" frame="true" align="right" spinBox="true" caption="1row, resolution 2.00Å" /> '''Structure of SSP-19,...) |
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| - | [[Image:1row.gif|left|200px]]<br /><applet load="1row" size=" | + | [[Image:1row.gif|left|200px]]<br /><applet load="1row" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1row, resolution 2.00Å" /> | caption="1row, resolution 2.00Å" /> | ||
'''Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans'''<br /> | '''Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Structural data are reported for SSP-19, a sperm-specific protein (SSP) | + | Structural data are reported for SSP-19, a sperm-specific protein (SSP) family member from Caenorhabditis elegans. The SSP family [also known as the major sperm protein-like (MSP-like) family] contains proteins with only 107-109 amino acids, compared with 127 amino acids in the major sperm protein (MSP) family. MSP, the most abundant protein in nematode sperm, forms a dynamic actin-like cytoskeleton that provides the framework for the nematode sperm motility. In vivo, MSP dimers polymerize to form filaments that are constructed from two helical strands, which assemble into larger macromolecular structures. Little is known about the SSP family and a similar function is inferred from sequence and structural homology [Pfam (Protein Families Database of Alignments and HMMs) and SCOP (Structural Classification of Proteins) classification]. Despite the overall structural homology, the monomer-monomer interactions in SSP-19 are strikingly different from the interactions in the two MSP canonic domains described previously. |
==About this Structure== | ==About this Structure== | ||
| - | 1ROW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http:// | + | 1ROW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROW OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Lin, G.]] | [[Category: Lin, G.]] | ||
[[Category: Lu, S.]] | [[Category: Lu, S.]] | ||
| - | [[Category: Luan, C | + | [[Category: Luan, C H.]] |
[[Category: Luo, D.]] | [[Category: Luo, D.]] | ||
[[Category: Luo, M.]] | [[Category: Luo, M.]] | ||
[[Category: Nagy, L.]] | [[Category: Nagy, L.]] | ||
[[Category: Qiu, S.]] | [[Category: Qiu, S.]] | ||
| - | [[Category: SECSG, Southeast | + | [[Category: SECSG, Southeast Collaboratory for Structural Genomics.]] |
[[Category: Schormann, N.]] | [[Category: Schormann, N.]] | ||
[[Category: Symersky, J.]] | [[Category: Symersky, J.]] | ||
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[[Category: structural genomics]] | [[Category: structural genomics]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:53:03 2008'' |
Revision as of 12:53, 21 February 2008
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Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans
Overview
Structural data are reported for SSP-19, a sperm-specific protein (SSP) family member from Caenorhabditis elegans. The SSP family [also known as the major sperm protein-like (MSP-like) family] contains proteins with only 107-109 amino acids, compared with 127 amino acids in the major sperm protein (MSP) family. MSP, the most abundant protein in nematode sperm, forms a dynamic actin-like cytoskeleton that provides the framework for the nematode sperm motility. In vivo, MSP dimers polymerize to form filaments that are constructed from two helical strands, which assemble into larger macromolecular structures. Little is known about the SSP family and a similar function is inferred from sequence and structural homology [Pfam (Protein Families Database of Alignments and HMMs) and SCOP (Structural Classification of Proteins) classification]. Despite the overall structural homology, the monomer-monomer interactions in SSP-19 are strikingly different from the interactions in the two MSP canonic domains described previously.
About this Structure
1ROW is a Single protein structure of sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.
Reference
Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans., Schormann N, Symersky J, Luo M, Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1840-5. Epub 2004, Sep 23. PMID:15388931
Page seeded by OCA on Thu Feb 21 14:53:03 2008
Categories: Caenorhabditis elegans | Single protein | Arabashi, A. | Bunzel, B. | Carson, M. | DeLucas, L. | Gray, R. | Li, S. | Lin, G. | Lu, S. | Luan, C H. | Luo, D. | Luo, M. | Nagy, L. | Qiu, S. | SECSG, Southeast Collaboratory for Structural Genomics. | Schormann, N. | Symersky, J. | Zhang, J. | Beta barrel | Protein structure initiative | Psi | Secsg | Southeast collaboratory for structural genomics | Structural genomics
