1rrz
From Proteopedia
(New page: 200px<br /><applet load="1rrz" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rrz" /> '''Solution structure of GlgS protein from E. c...) |
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| - | [[Image:1rrz.gif|left|200px]]<br /><applet load="1rrz" size=" | + | [[Image:1rrz.gif|left|200px]]<br /><applet load="1rrz" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1rrz" /> | caption="1rrz" /> | ||
'''Solution structure of GlgS protein from E. coli'''<br /> | '''Solution structure of GlgS protein from E. coli'''<br /> | ||
==Overview== | ==Overview== | ||
| - | BACKGROUND: The Escherichia coli protein GlgS is up-regulated in response | + | BACKGROUND: The Escherichia coli protein GlgS is up-regulated in response to starvation stress and its overexpression was shown to stimulate glycogen synthesis. RESULTS: We solved the structure of GlgS from E. coli, a member of an enterobacterial protein family. The protein structure represents a bundle of three alpha-helices with a short hydrophobic helix sandwiched between two long amphipathic helices. CONCLUSION: GlgS shows structural homology to Huntingtin, elongation factor 3, protein phosphatase 2A, TOR1 motif domains and tetratricopeptide repeats, suggesting a possible role in protein-protein interactions. |
==About this Structure== | ==About this Structure== | ||
| - | 1RRZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http:// | + | 1RRZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RRZ OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: BSGI, Montreal-Kingston | + | [[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]] |
[[Category: Gehring, K.]] | [[Category: Gehring, K.]] | ||
[[Category: Kozlov, G.]] | [[Category: Kozlov, G.]] | ||
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[[Category: structural genomics]] | [[Category: structural genomics]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:53:56 2008'' |
Revision as of 12:53, 21 February 2008
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Solution structure of GlgS protein from E. coli
Overview
BACKGROUND: The Escherichia coli protein GlgS is up-regulated in response to starvation stress and its overexpression was shown to stimulate glycogen synthesis. RESULTS: We solved the structure of GlgS from E. coli, a member of an enterobacterial protein family. The protein structure represents a bundle of three alpha-helices with a short hydrophobic helix sandwiched between two long amphipathic helices. CONCLUSION: GlgS shows structural homology to Huntingtin, elongation factor 3, protein phosphatase 2A, TOR1 motif domains and tetratricopeptide repeats, suggesting a possible role in protein-protein interactions.
About this Structure
1RRZ is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Structure of GlgS from Escherichia coli suggests a role in protein-protein interactions., Kozlov G, Elias D, Cygler M, Gehring K, BMC Biol. 2004 May 25;2:10. PMID:15161493
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