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Lac repressor
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==What is the lac repressor?== | ==What is the lac repressor?== | ||
| - | Repressors are proteins that inhibit the expression of genes; that is, they inhibit the transcription of messenger RNA from their target genes. The lac repressor controls the expression of bacterial enzymes involved in the metabolism of of the sugar lactose. | + | Repressors are proteins that inhibit the expression of genes; that is, they inhibit the transcription of messenger RNA from their target genes. Repressors act on specific genes or groups of genes by recognizing specific sequences of DNA. The lac repressor controls the expression of bacterial enzymes involved in the metabolism of of the sugar lactose. It, and the group of genes it controls, called an [http://en.wikipedia.org/wiki/Operon operon], were the first such gene regulatory system to be discovered. |
For a general introduction to the lac repressor, please see David Goodsell's [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb39_1.html Introduction to the lac repressor] in his series [[Molecule of the Month]], and the article in Wikipedia on the [http://en.wikipedia.org/wiki/Lac_repressor lac repressor]. | For a general introduction to the lac repressor, please see David Goodsell's [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb39_1.html Introduction to the lac repressor] in his series [[Molecule of the Month]], and the article in Wikipedia on the [http://en.wikipedia.org/wiki/Lac_repressor lac repressor]. | ||
Revision as of 22:21, 5 October 2008
What is the lac repressor?
Repressors are proteins that inhibit the expression of genes; that is, they inhibit the transcription of messenger RNA from their target genes. Repressors act on specific genes or groups of genes by recognizing specific sequences of DNA. The lac repressor controls the expression of bacterial enzymes involved in the metabolism of of the sugar lactose. It, and the group of genes it controls, called an operon, were the first such gene regulatory system to be discovered.
For a general introduction to the lac repressor, please see David Goodsell's Introduction to the lac repressor in his series Molecule of the Month, and the article in Wikipedia on the lac repressor.
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Eric Martz, Michal Harel, Alexander Berchansky, Joel L. Sussman, Karsten Theis, Henry Jakubowski, David Canner, Eran Hodis
