3e64
From Proteopedia
| Line 1: | Line 1: | ||
| - | + | {{Seed}} | |
| + | [[Image:3e64.jpg|left|200px]] | ||
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3e64", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| + | or leave the SCENE parameter empty for the default display. | ||
| + | --> | ||
| + | {{STRUCTURE_3e64| PDB=3e64 | SCENE= }} | ||
| - | + | ===Fragment based discovery of JAK-2 inhibitors=== | |
| - | Description: Fragment based discovery of JAK-2 inhibitors | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct | + | ==Disease== |
| + | Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myelofibrosis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myeloproliferative disorder with erythrocytosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Polycythemia vera OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Thrombocythemia, essential OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Budd-Chiari syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]] | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3E64 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E64 OCA]. | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific protein-tyrosine kinase]] | ||
| + | [[Category: Single protein]] | ||
| + | [[Category: Antonysamy, S S.]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Chromosomal rearrangement]] | ||
| + | [[Category: Disease mutation]] | ||
| + | [[Category: Drug discovery]] | ||
| + | [[Category: Fragment based]] | ||
| + | [[Category: Jak2]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Proto-oncogene]] | ||
| + | [[Category: Sh2 domain]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Tyrosine-protein kinase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15:27:54 2008'' | ||
Revision as of 13:27, 15 October 2008
Fragment based discovery of JAK-2 inhibitors
Disease
Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]
About this Structure
3E64 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Oct 15 15:27:54 2008
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Single protein | Antonysamy, S S. | Atp-binding | Chromosomal rearrangement | Disease mutation | Drug discovery | Fragment based | Jak2 | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Proto-oncogene | Sh2 domain | Transferase | Tyrosine-protein kinase
