3ens

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ens.jpg|left|200px]]
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The entry 3ens is ON HOLD
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{{STRUCTURE_3ens| PDB=3ens | SCENE= }}
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Authors: Klei, H.E.
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===Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate===
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Description: Crystal structure of human FXA in complex with (S,E)-methyl 3-(3-chloro-1h-indol-7-ylamino)-2-cyano-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-ylamino)acrylate
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 8 09:20:43 2008''
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{{ABSTRACT_PUBMED_18998662}}
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==About this Structure==
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3ENS is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ENS OCA].
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==Reference==
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Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors., Shi Y, Sitkoff D, Zhang J, Klei HE, Kish K, Liu EC, Hartl KS, Seiler SM, Chang M, Huang C, Youssef S, Steinbacher TE, Schumacher WA, Grazier N, Pudzianowski A, Apedo A, Discenza L, Yanchunas J Jr, Stein PD, Atwal KS, J Med Chem. 2008 Nov 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18998662 18998662]
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[[Category: Coagulation factor Xa]]
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[[Category: Homo sapiens]]
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[[Category: Klei, H E.]]
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[[Category: Blood clotting]]
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[[Category: Blood coagulation factor]]
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[[Category: Calcium]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Egf-like domain]]
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[[Category: Epidermal growth factor like domain]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Hydroxylation]]
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[[Category: Polymorphism]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 10:33:40 2008''

Revision as of 08:33, 31 December 2008

Image:3ens.jpg

Template:STRUCTURE 3ens

Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate

Template:ABSTRACT PUBMED 18998662

About this Structure

3ENS is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors., Shi Y, Sitkoff D, Zhang J, Klei HE, Kish K, Liu EC, Hartl KS, Seiler SM, Chang M, Huang C, Youssef S, Steinbacher TE, Schumacher WA, Grazier N, Pudzianowski A, Apedo A, Discenza L, Yanchunas J Jr, Stein PD, Atwal KS, J Med Chem. 2008 Nov 11. PMID:18998662

Page seeded by OCA on Wed Dec 31 10:33:40 2008

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OCA

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