2zn7

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==Disease==
==Disease==
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Known disease associated with this structure: Abdominal body fat distribution, modifier of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]], Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]]
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Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]]
==About this Structure==
==About this Structure==
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2ZN7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZN7 OCA].
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2ZN7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZN7 OCA].
==Reference==
==Reference==
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Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24., Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J, ChemMedChem. 2008 Oct;3(10):1525-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18798205 18798205]
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<ref group="xtra">PMID:18798205</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Single protein]]
 
[[Category: Wu, J.]]
[[Category: Wu, J.]]
[[Category: Xu, W.]]
[[Category: Xu, W.]]
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[[Category: Ptp1b]]
[[Category: Ptp1b]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 29 09:47:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:48:38 2009''

Revision as of 02:48, 17 February 2009

Template:STRUCTURE 2zn7

Contents

CRYSTAL STRUCTURES OF PTP1B-Inhibitor Complexes

Disease

Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[176885]

About this Structure

2ZN7 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J. Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24. ChemMedChem. 2008 Oct;3(10):1525-9. PMID:18798205 doi:10.1002/cmdc.200800188

Page seeded by OCA on Tue Feb 17 04:48:38 2009

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