2w1h

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(New page: '''Unreleased structure''' The entry 2w1h is ON HOLD until Paper Publication Authors: Howard, S., Berdini, V., Boulstridge, J.A., Carr, M.G., Cross, D.M., Curry, J., Devine, L.A., Early...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:2w1h.jpg|left|200px]]
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The entry 2w1h is ON HOLD until Paper Publication
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{{STRUCTURE_2w1h| PDB=2w1h | SCENE= }}
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Authors: Howard, S., Berdini, V., Boulstridge, J.A., Carr, M.G., Cross, D.M., Curry, J., Devine, L.A., Early, T.R., Fazal, L., Gill, A.L., Heathcote, M., Maman, S., Matthews, J.E., McMenamin, R.L., Navarro, E.F., O'Brien, M.A., O'Reilly, M., Rees, D.C., Reule, M., Tisi, D., Williams, G., Vinkovic, M., Wyatt, P.G.
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===FRAGMENT-BASED DISCOVERY OF THE PYRAZOL-4-YL UREA (AT9283), A MULTI-TARGETED KINASE INHIBITOR WITH POTENT AURORA KINASE ACTIVITY===
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Description: Fragment-Based Discovery of the Pyrazol-4-yl urea (AT9283), a Multi-targeted Kinase Inhibitor with Potent Aurora Kinase Activity
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 29 10:19:38 2008''
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{{ABSTRACT_PUBMED_19143567}}
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==About this Structure==
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2W1H is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1H OCA].
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==Reference==
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<ref group="xtra">PMID:19143567</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Berdini, V.]]
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[[Category: Boulstridge, J A.]]
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[[Category: Brien, M A.O.]]
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[[Category: Carr, M G.]]
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[[Category: Cross, D M.]]
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[[Category: Curry, J.]]
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[[Category: Devine, L A.]]
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[[Category: Early, T R.]]
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[[Category: Fazal, L.]]
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[[Category: Gill, A L.]]
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[[Category: Heathcote, M.]]
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[[Category: Howard, S.]]
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[[Category: Maman, S.]]
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[[Category: Matthews, J E.]]
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[[Category: Mcmenamin, R L.]]
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[[Category: Navarro, E F.]]
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[[Category: Rees, D C.]]
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[[Category: Reilly, M O.]]
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[[Category: Reule, M.]]
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[[Category: Tisi, D.]]
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[[Category: Vinkovic, M.]]
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[[Category: Williams, G.]]
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[[Category: Wyatt, P G.]]
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[[Category: Atp-binding]]
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[[Category: Cell cycle]]
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[[Category: Cell division]]
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[[Category: Fragment screening]]
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[[Category: Kinase]]
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[[Category: Mitosis]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Structure based drug design]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:39:00 2009''

Revision as of 07:39, 28 January 2009

Image:2w1h.jpg

Template:STRUCTURE 2w1h

FRAGMENT-BASED DISCOVERY OF THE PYRAZOL-4-YL UREA (AT9283), A MULTI-TARGETED KINASE INHIBITOR WITH POTENT AURORA KINASE ACTIVITY

Template:ABSTRACT PUBMED 19143567

About this Structure

2W1H is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Howard S, Berdini V, Boulstridge JA, Carr MG, Cross DM, Curry J, Devine LA, Early TR, Fazal L, Gill AL, Heathcote M, Maman S, Matthews JE, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Rees DC, Reule M, Tisi D, Williams G, Vinkovic M, Wyatt PG. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. J Med Chem. 2009 Jan 22;52(2):379-88. PMID:19143567 doi:10.1021/jm800984v

Page seeded by OCA on Wed Jan 28 09:39:00 2009

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