3e6p

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3e6p.jpg|left|200px]]
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The entry 3e6p is ON HOLD until Nov 18 2009
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{{STRUCTURE_3e6p| PDB=3e6p | SCENE= }}
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Authors: Papaconstantinou, M.E., Gandhi, P., Chen, Z., Bah, A., Di Cera, E.
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===Crystal structure of human meizothrombin desF1===
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Description: Crystal structure of human meizothrombin desF1
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 5 11:40:45 2008''
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(as it appears on PubMed at http://www.pubmed.gov), where 18854941 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18854941}}
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==Disease==
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Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
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==About this Structure==
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3E6P is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E6P OCA].
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==Reference==
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Na(+) binding to meizothrombin desF1., Papaconstantinou ME, Gandhi PS, Chen Z, Bah A, Di Cera E, Cell Mol Life Sci. 2008 Nov;65(22):3688-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18854941 18854941]
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New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK., Martin PD, Malkowski MG, Box J, Esmon CT, Edwards BF, Structure. 1997 Dec 15;5(12):1681-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9438869 9438869]
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[[Category: Homo sapiens]]
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[[Category: Thrombin]]
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[[Category: Bah, A.]]
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[[Category: Cera, E Di.]]
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[[Category: Chen, Z.]]
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[[Category: Gandhi, P.]]
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[[Category: Papaconstantinou, M E.]]
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[[Category: Acute phase]]
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[[Category: Allostery]]
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[[Category: Blood coagulation]]
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[[Category: Calcium]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disease mutation]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Kringle]]
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[[Category: Linkage]]
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[[Category: Meizothrombin]]
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[[Category: Na+ binding]]
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[[Category: Pharmaceutical]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Thrombin]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:45:00 2008''

Revision as of 05:45, 20 November 2008

Image:3e6p.jpg

Template:STRUCTURE 3e6p

Contents

Crystal structure of human meizothrombin desF1

Template:ABSTRACT PUBMED 18854941

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

3E6P is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Na(+) binding to meizothrombin desF1., Papaconstantinou ME, Gandhi PS, Chen Z, Bah A, Di Cera E, Cell Mol Life Sci. 2008 Nov;65(22):3688-97. PMID:18854941

New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK., Martin PD, Malkowski MG, Box J, Esmon CT, Edwards BF, Structure. 1997 Dec 15;5(12):1681-93. PMID:9438869

Page seeded by OCA on Thu Nov 20 07:45:00 2008

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