3ela
From Proteopedia
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- | [[Image:3ela. | + | [[Image:3ela.png|left|200px]] |
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==About this Structure== | ==About this Structure== | ||
- | 3ELA is a | + | 3ELA is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELA OCA]. |
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:18640965</ref><references group="xtra"/> | |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Protein complex]] | ||
[[Category: Bjelke, J R.]] | [[Category: Bjelke, J R.]] | ||
[[Category: Fodje, M.]] | [[Category: Fodje, M.]] | ||
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[[Category: Zymogen]] | [[Category: Zymogen]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:17:26 2009'' |
Revision as of 10:17, 17 February 2009
Contents |
Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor
Template:ABSTRACT PUBMED 18640965
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
3ELA is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E. Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity. J Biol Chem. 2008 Sep 19;283(38):25863-70. Epub 2008 Jul 17. PMID:18640965 doi:10.1074/jbc.M800841200
Page seeded by OCA on Tue Feb 17 12:17:26 2009
Categories: Coagulation factor VIIa | Homo sapiens | Bjelke, J R. | Fodje, M. | Svensson, L A. | Allosteric regulation | Allostery | Alternative splicing | Blood clotting | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disease mutation | Egf-like domain | Exosite | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Lipoprotein | Membrane | Palmitate | Pharmaceutical | Polymorphism | Protease | Secreted | Serine protease | Transmembrane | Zymogen