2w26

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{{Seed}}
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[[Image:2w26.jpg|left|200px]]
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==Reference==
==Reference==
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Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor., Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E, J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16161994 16161994]
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<ref group="xtra">PMID:16161994</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lampe, T.]]
[[Category: Lampe, T.]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 12 10:43:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:41:33 2009''

Revision as of 15:41, 16 February 2009

Template:STRUCTURE 2w26

FACTOR XA IN COMPLEX WITH BAY59-7939

Template:ABSTRACT PUBMED 16161994

About this Structure

2W26 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:16161994 doi:10.1021/jm050101d

Page seeded by OCA on Mon Feb 16 17:41:33 2009

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