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2uue
From Proteopedia
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===REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS=== | ===REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS=== | ||
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| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_17051658}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 17051658 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_17051658}} | ||
==About this Structure== | ==About this Structure== | ||
2UUE is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2c5t 2c5t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUE OCA]. | 2UUE is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2c5t 2c5t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUE OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:17051658</ref><ref group="xtra">PMID:16492568</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:56:57 2009'' |
Revision as of 10:56, 25 March 2009
REPLACE: A STRATEGY FOR ITERATIVE DESIGN OF CYCLIN BINDING GROOVE INHIBITORS
Template:ABSTRACT PUBMED 17051658
About this Structure
2UUE is a 6 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 2c5t. Full crystallographic information is available from OCA.
Reference
- Andrews MJ, Kontopidis G, McInnes C, Plater A, Innes L, Cowan A, Jewsbury P, Fischer PM. REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors. Chembiochem. 2006 Dec;7(12):1909-15. PMID:17051658 doi:10.1002/cbic.200600189
- Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568 doi:http://dx.doi.org/10.1016/j.chembiol.2005.11.011
Page seeded by OCA on Wed Mar 25 12:56:57 2009
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Andrews, M J. | Cowan, A. | Fischer, P M. | Innes, L. | Jewsbury, P. | Kontopidis, G. | Mcinnes, C. | Plater, A. | Active | Atp-binding | Cdk2 | Cell cycle | Cell division | Cyclin | Cyclin groove | Inhibition | Kinase | Mitosis | Nonpeptide | Nucleotide-binding | Phosphorylation | Polymorphism | Serine/threonine-protein kinase | Transferase
