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Transcription Termination Factor Rho

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'''Transcription termination factor Rho''' is a ring-shaped RNA-DNA '''helicase''' that induces release of transcription complexes at specific locci of bacterial genomes. Several structures of Rho in various liganted states haven been solved by X-ray cristallography by the Berger lab (Berkeley). Here is one representation showing the Rho hexamer in a closed state and with RNA fragments occupying both its primary and secondary binding sites.
'''Transcription termination factor Rho''' is a ring-shaped RNA-DNA '''helicase''' that induces release of transcription complexes at specific locci of bacterial genomes. Several structures of Rho in various liganted states haven been solved by X-ray cristallography by the Berger lab (Berkeley). Here is one representation showing the Rho hexamer in a closed state and with RNA fragments occupying both its primary and secondary binding sites.
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<applet load='Rho1.pdb' size='300' frame='true' align='right' caption='Insert caption here' /
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<applet load='Rho1.pdb' size='300' frame='true' align='right' scene='Transcription_Termination_Factor_Rho/Rho_closed_1/2'>
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<scene name='Transcription_Termination_Factor_Rho/Rho_closed_1/2'>TextToBeDisplayed</scene>
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Revision as of 12:59, 19 November 2008


Transcription termination factor Rho is a ring-shaped RNA-DNA helicase that induces release of transcription complexes at specific locci of bacterial genomes. Several structures of Rho in various liganted states haven been solved by X-ray cristallography by the Berger lab (Berkeley). Here is one representation showing the Rho hexamer in a closed state and with RNA fragments occupying both its primary and secondary binding sites.

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