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3bdj

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[[Image:3bdj.png|left|200px]]
[[Image:3bdj.png|left|200px]]
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==About this Structure==
==About this Structure==
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3BDJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BDJ OCA].
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[[3bdj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BDJ OCA].
==Reference==
==Reference==
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Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol., Okamoto K, Eger BT, Nishino T, Pai EF, Nishino T, Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):888-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18600558 18600558]
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<ref group="xtra">PMID:18600558</ref><ref group="xtra">PMID:11796116</ref><ref group="xtra">PMID:15148401</ref><ref group="xtra">PMID:15190124</ref><ref group="xtra">PMID:12421831</ref><references group="xtra"/>
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Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus., Truglio JJ, Theis K, Leimkuhler S, Rappa R, Rajagopalan KV, Kisker C, Structure. 2002 Jan;10(1):115-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11796116 11796116]
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The crystal structure of xanthine oxidoreductase during catalysis: implications for reaction mechanism and enzyme inhibition., Okamoto K, Matsumoto K, Hille R, Eger BT, Pai EF, Nishino T, Proc Natl Acad Sci U S A. 2004 May 25;101(21):7931-6. Epub 2004 May 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15148401 15148401]
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Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion., Fukunari A, Okamoto K, Nishino T, Eger BT, Pai EF, Kamezawa M, Yamada I, Kato N, J Pharmacol Exp Ther. 2004 Nov;311(2):519-28. Epub 2004 Jun 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15190124 15190124]
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An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition., Okamoto K, Eger BT, Nishino T, Kondo S, Pai EF, Nishino T, J Biol Chem. 2003 Jan 17;278(3):1848-55. Epub 2002 Nov 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12421831 12421831]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Eger, B T.]]
[[Category: Eger, B T.]]
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[[Category: Xanthine oxidase]]
[[Category: Xanthine oxidase]]
[[Category: Xanthine oxidoreductase]]
[[Category: Xanthine oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Dec 5 09:58:31 2008''
 

Revision as of 19:23, 14 March 2011

Image:3bdj.png

Template:STRUCTURE 3bdj

Crystal Structure of Bovine Milk Xanthine Dehydrogenase with a Covalently Bound Oxipurinol Inhibitor

Template:ABSTRACT PUBMED 18600558

About this Structure

3bdj is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Okamoto K, Eger BT, Nishino T, Pai EF, Nishino T. Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol. Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):888-93. PMID:18600558 doi:794699692
  • Truglio JJ, Theis K, Leimkuhler S, Rappa R, Rajagopalan KV, Kisker C. Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus. Structure. 2002 Jan;10(1):115-25. PMID:11796116
  • Okamoto K, Matsumoto K, Hille R, Eger BT, Pai EF, Nishino T. The crystal structure of xanthine oxidoreductase during catalysis: implications for reaction mechanism and enzyme inhibition. Proc Natl Acad Sci U S A. 2004 May 25;101(21):7931-6. Epub 2004 May 17. PMID:15148401 doi:10.1073/pnas.0400973101
  • Fukunari A, Okamoto K, Nishino T, Eger BT, Pai EF, Kamezawa M, Yamada I, Kato N. Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion. J Pharmacol Exp Ther. 2004 Nov;311(2):519-28. Epub 2004 Jun 9. PMID:15190124 doi:10.1124/jpet.104.070433
  • Okamoto K, Eger BT, Nishino T, Kondo S, Pai EF, Nishino T. An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition. J Biol Chem. 2003 Jan 17;278(3):1848-55. Epub 2002 Nov 5. PMID:12421831 doi:10.1074/jbc.M208307200

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