3f5p
From Proteopedia
| Line 23: | Line 23: | ||
==About this Structure== | ==About this Structure== | ||
| - | 3F5P is a | + | 3F5P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F5P OCA]. |
==Reference== | ==Reference== | ||
| Line 31: | Line 31: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
| - | [[Category: | + | [[Category: Single protein]] |
| - | [[Category: | + | [[Category: Pdbx_ordinal=, <PDBx:audit_author.]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
| Line 53: | Line 49: | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 7 20:04:46 2009'' |
Revision as of 17:35, 8 January 2009
Contents |
Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor
Template:ABSTRACT PUBMED 19041240
Disease
Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147370]
About this Structure
3F5P is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Miller LM, Mayer SC, Berger DM, Boschelli DH, Boschelli F, Di L, Du X, Dutia M, Floyd MB, Johnson M, Kenny CH, Krishnamurthy G, Moy F, Petusky S, Tkach D, Torres N, Wu B, Xu W, Bioorg Med Chem Lett. 2009 Jan 1;19(1):62-6. Epub 2008 Nov 17. PMID:19041240
Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W, Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
Page seeded by OCA on Wed Jan 7 20:04:46 2009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Atp-binding | Cleavage on pair of basic residue | Disease mutation | Glycoprotein | Igf-1r | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Protein-inhibitor complex | Receptor | Transferase | Transmembrane | Tyrosine kinase | Tyrosine-protein kinase
