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3ekk

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==About this Structure==
==About this Structure==
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3EKK is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EKK OCA].
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3EKK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EKK OCA].
==Reference==
==Reference==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Atkins, C.]]
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[[Category: Single protein]]
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[[Category: Chamberlain, S.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Deanda, F.]]
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[[Category: Dumble, M.]]
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[[Category: Gerding, R.]]
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[[Category: Groy, A.]]
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[[Category: Korenchuk, S.]]
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[[Category: Kumar, R.]]
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[[Category: Lei, H.]]
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[[Category: Mook, R.]]
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[[Category: Moorthy, G.]]
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[[Category: Redman, A.]]
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[[Category: Rowland, J.]]
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[[Category: Sabbatini, P.]]
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[[Category: Shewchuk, L.]]
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[[Category: Alternative splicing]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 7 08:10:52 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 7 20:06:42 2009''

Revision as of 17:37, 8 January 2009

Image:3ekk.png

Template:STRUCTURE 3ekk

Contents

Insulin receptor kinase complexed with an inhibitor

Template:ABSTRACT PUBMED 19056263

Disease

Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]

About this Structure

3EKK is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase., Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB, Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]

Page seeded by OCA on Wed Jan 7 20:06:42 2009

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