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3elj

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==About this Structure==
==About this Structure==
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3ELJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELJ OCA].
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3ELJ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELJ OCA].
==Reference==
==Reference==
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Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity., Chamberlain SD, Redman AM, Wilson JW, Deanda F, Shotwell JB, Gerding R, Lei H, Yang B, Stevens KL, Hassell AM, Shewchuk LM, Leesnitzer MA, Smith JL, Sabbatini P, Atkins C, Groy A, Rowand JL, Kumar R, Mook RA Jr, Moorthy G, Patnaik S, Bioorg Med Chem Lett. 2009 Jan 15;19(2):360-4. Epub 2008 Nov 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19071018 19071018]
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<ref group="xtra">PMID:19071018</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: Single protein]]
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[[Category: Atkins, C.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Chamberlain, S.]]
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[[Category: Deanda, F.]]
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[[Category: Dumble, M.]]
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[[Category: Gerding, R.]]
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[[Category: Groy, A.]]
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[[Category: Korenchuk, S.]]
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[[Category: Kumar, R.]]
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[[Category: Lei, H.]]
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[[Category: Mook, R.]]
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[[Category: Moorthy, G.]]
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[[Category: Mosley, J.]]
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[[Category: Redman, A.]]
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[[Category: Rowland, J.]]
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[[Category: Shewchuk, L.]]
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[[Category: Vicentini, G.]]
[[Category: Alternative splicing]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 12:03:25 2010''

Revision as of 08:54, 22 September 2010

Image:3elj.png

Template:STRUCTURE 3elj

Jnk1 complexed with a bis-anilino-pyrrolopyrimidine inhibitor.

Template:ABSTRACT PUBMED 19071018

About this Structure

3ELJ is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chamberlain SD, Redman AM, Wilson JW, Deanda F, Shotwell JB, Gerding R, Lei H, Yang B, Stevens KL, Hassell AM, Shewchuk LM, Leesnitzer MA, Smith JL, Sabbatini P, Atkins C, Groy A, Rowand JL, Kumar R, Mook RA Jr, Moorthy G, Patnaik S. Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity. Bioorg Med Chem Lett. 2009 Jan 15;19(2):360-4. Epub 2008 Nov 24. PMID:19071018 doi:S0960-894X(08)01461-3

Page seeded by OCA on Wed Sep 22 12:03:25 2010

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