3fkt

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3fkt.jpg|left|200px]]
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The entry 3fkt is ON HOLD until Paper Publication
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{{STRUCTURE_3fkt| PDB=3fkt | SCENE= }}
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Authors: Munshi, S.
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===Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor===
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Description: Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 14 12:54:30 2009''
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{{ABSTRACT_PUBMED_18811140}}
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==About this Structure==
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3FKT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3e3w 3e3w]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FKT OCA].
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==Reference==
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<ref group="xtra">PMID:18811140</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Munshi, S.]]
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[[Category: Alternative splicing]]
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[[Category: Aspartyl protease]]
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[[Category: Bace]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Transmembrane]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 10:48:24 2009''

Revision as of 08:48, 21 January 2009

Image:3fkt.jpg

Template:STRUCTURE 3fkt

Crystal Structure of Human Beta Secretase Complexed with Spiropiperdine Iminohydantoin Inhibitor

Template:ABSTRACT PUBMED 18811140

About this Structure

3FKT is a 1 chain structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3e3w. Full crystallographic information is available from OCA.

Reference

  • Barrow JC, Stauffer SR, Rittle KE, Ngo PL, Yang Z, Selnick HG, Graham SL, Munshi S, McGaughey GB, Holloway MK, Simon AJ, Price EA, Sankaranarayanan S, Colussi D, Tugusheva K, Lai MT, Espeseth AS, Xu M, Huang Q, Wolfe A, Pietrak B, Zuck P, Levorse DA, Hazuda D, Vacca JP. Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase. J Med Chem. 2008 Oct 23;51(20):6259-62. Epub 2008 Sep 24. PMID:18811140 doi:10.1021/jm800914n

Page seeded by OCA on Wed Jan 21 10:48:24 2009

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