2w2o

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==About this Structure==
==About this Structure==
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2W2O is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W2O OCA].
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2W2O is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W2O OCA].
==Reference==
==Reference==
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Structural and biochemical characterization of the wild type PCSK9/EGF-AB complex and natural FH mutants., Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfi A, J Biol Chem. 2008 Nov 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19001363 19001363]
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<ref group="xtra">PMID:19001363</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
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[[Category: Baysarowich, J.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Bottomley, M J.]]
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[[Category: Calzetta, A.]]
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[[Category: Carfi, A.]]
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[[Category: Cirillo, A.]]
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[[Category: Cubbon, R M.]]
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[[Category: Cummings, R T.]]
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[[Category: Fisher, T S.]]
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[[Category: Francesco, R De.]]
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[[Category: Mattu, M.]]
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[[Category: Noto, A.]]
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[[Category: Orsatti, L.]]
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[[Category: Ruggeri, L.]]
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[[Category: Santoro, J C.]]
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[[Category: Sitlani, A.]]
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[[Category: Sparrow, C P.]]
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[[Category: Surdo, P Lo.]]
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[[Category: Talamo, F.]]
[[Category: Cardiovascular disease]]
[[Category: Cardiovascular disease]]
[[Category: Egf]]
[[Category: Egf]]
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[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 14 20:07:38 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 28 09:38:14 2009''

Revision as of 07:38, 28 October 2009

Image:2w2o.png

Template:STRUCTURE 2w2o

PCSK9-DELTAC D374Y MUTANT BOUND TO WT EGF-A OF LDLR

Template:ABSTRACT PUBMED 19001363

About this Structure

2W2O is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfi A. Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants. J Biol Chem. 2009 Jan 9;284(2):1313-23. Epub 2008 Nov 10. PMID:19001363 doi:10.1074/jbc.M808363200

Page seeded by OCA on Wed Oct 28 09:38:14 2009

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