2w2m

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==About this Structure==
==About this Structure==
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2W2M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W2M OCA].
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2W2M is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W2M OCA].
==Reference==
==Reference==
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Structural and biochemical characterization of the wild type PCSK9/EGF-AB complex and natural FH mutants., Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfi A, J Biol Chem. 2008 Nov 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19001363 19001363]
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<ref group="xtra">PMID:19001363</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
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[[Category: Baysarowich, J.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Bottomley, M J.]]
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[[Category: Calzetta, A.]]
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[[Category: Carfi, A.]]
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[[Category: Cirillo, A.]]
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[[Category: Cubbon, R M.]]
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[[Category: Cummings, R T.]]
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[[Category: Fisher, T S.]]
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[[Category: Francesco, R De.]]
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[[Category: Mattu, M.]]
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[[Category: Noto, A.]]
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[[Category: Orsatti, L.]]
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[[Category: Ruggeri, L.]]
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[[Category: Santoro, J C.]]
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[[Category: Sitlani, A.]]
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[[Category: Sparrow, C P.]]
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[[Category: Surdo, P Lo.]]
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[[Category: Talamo, F.]]
[[Category: Cardiovascular disease]]
[[Category: Cardiovascular disease]]
[[Category: Egf]]
[[Category: Egf]]
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[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 14 20:34:27 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:32:49 2010''

Revision as of 08:23, 22 September 2010

Image:2w2m.png

Template:STRUCTURE 2w2m

WT PCSK9-DELTAC BOUND TO WT EGF-A OF LDLR

Template:ABSTRACT PUBMED 19001363

About this Structure

2W2M is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfi A. Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants. J Biol Chem. 2009 Jan 9;284(2):1313-23. Epub 2008 Nov 10. PMID:19001363 doi:10.1074/jbc.M808363200

Page seeded by OCA on Wed Sep 22 11:32:49 2010

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