2zjk

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[[Image:2zjk.png|left|200px]]
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[[Image:2zjk.jpg|left|200px]]
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{{STRUCTURE_2zjk| PDB=2zjk | SCENE= }}
{{STRUCTURE_2zjk| PDB=2zjk | SCENE= }}
===Crystal structure of the human BACE1 catalytic domain in complex with 4-(4-fluoro-benzyl)-piperazine-2-carboxylic acid(3-mercapto-propyl)-amide===
===Crystal structure of the human BACE1 catalytic domain in complex with 4-(4-fluoro-benzyl)-piperazine-2-carboxylic acid(3-mercapto-propyl)-amide===
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{{ABSTRACT_PUBMED_019284778}}
==About this Structure==
==About this Structure==
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2ZJK is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJK OCA].
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[[2zjk]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZJK OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
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==Reference==
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<ref group="xtra">PMID:019284778</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Randal, M.]]
[[Category: Randal, M.]]
[[Category: Romanowski, M J.]]
[[Category: Romanowski, M J.]]
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[[Category: Alternative splicing]]
 
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace1]]
[[Category: Bace1]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 21 10:40:34 2009''
 

Revision as of 13:50, 27 July 2012

Image:2zjk.png

Template:STRUCTURE 2zjk

Contents

Crystal structure of the human BACE1 catalytic domain in complex with 4-(4-fluoro-benzyl)-piperazine-2-carboxylic acid(3-mercapto-propyl)-amide

Template:ABSTRACT PUBMED 019284778

About this Structure

2zjk is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Yang W, Fucini RV, Fahr BT, Randal M, Lind KE, Lam MB, Lu W, Lu Y, Cary DR, Romanowski MJ, Colussi D, Pietrak B, Allison TJ, Munshi SK, Penny DM, Pham P, Sun J, Thomas AE, Wilkinson JM, Jacobs JW, McDowell RS, Ballinger MD. Fragment-based discovery of nonpeptidic BACE-1 inhibitors using tethering. Biochemistry. 2009 Jun 2;48(21):4488-96. PMID:19284778 doi:10.1021/bi900017q

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