2zm4
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2ZM4 is a | + | 2ZM4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM4 OCA]. |
==Reference== | ==Reference== | ||
| - | + | The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase., Ozawa T, Tsuji E, Ozawa M, Handa C, Mukaiyama H, Nishimura T, Kobayashi S, Okazaki K, Bioorg Med Chem. 2008 Dec 15;16(24):10311-8. Epub 2008 Oct 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18977146 18977146] | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
| - | [[Category: | + | [[Category: Single protein]] |
| + | [[Category: Pdbx_ordinal=, <PDBx:audit_author.]] | ||
[[Category: Alternative splicing]] | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 20:05:25 2009'' |
Revision as of 05:06, 6 February 2009
Contents |
Crystal structure of imidazo quinoxaline 1 bound to the kinase domain of human LCK, activated form (auto-phosphorylated on TYR394)
Template:ABSTRACT PUBMED 18977146
Disease
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]
About this Structure
2ZM4 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase., Ozawa T, Tsuji E, Ozawa M, Handa C, Mukaiyama H, Nishimura T, Kobayashi S, Okazaki K, Bioorg Med Chem. 2008 Dec 15;16(24):10311-8. Epub 2008 Oct 22. PMID:18977146[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
Page seeded by OCA on Wed Feb 4 20:05:25 2009
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Single protein | Alternative splicing | Atp-binding | Chromosomal rearrangement | Cytoplasm | Disease mutation | Host-virus interaction | Lipoprotein | Membrane | Myristate | Nucleotide-binding | Palmitate | Phosphoprotein | Phosphorylation | Proto-oncogene | Sh2 domain | Sh3 domain | Signal transduction | Transferase | Tyrosine-protein kinase
