2zm4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 23: Line 23:
==About this Structure==
==About this Structure==
-
2ZM4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM4 OCA].
+
2ZM4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZM4 OCA].
==Reference==
==Reference==
-
The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase., Ozawa T, Tsuji E, Ozawa M, Handa C, Mukaiyama H, Nishimura T, Kobayashi S, Okazaki K, Bioorg Med Chem. 2008 Dec 15;16(24):10311-8. Epub 2008 Oct 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18977146 18977146]
+
<ref group="xtra">PMID:18977146</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
-
[[Category: Single protein]]
+
[[Category: Tsuji, E.]]
-
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
+
[[Category: Alternative splicing]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
Line 51: Line 50:
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 20:05:25 2009''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:02:16 2009''

Revision as of 06:02, 18 February 2009

Image:2zm4.png

Template:STRUCTURE 2zm4

Contents

Crystal structure of imidazo quinoxaline 1 bound to the kinase domain of human LCK, activated form (auto-phosphorylated on TYR394)

Template:ABSTRACT PUBMED 18977146

Disease

Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]

About this Structure

2ZM4 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ozawa T, Tsuji E, Ozawa M, Handa C, Mukaiyama H, Nishimura T, Kobayashi S, Okazaki K. The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase. Bioorg Med Chem. 2008 Dec 15;16(24):10311-8. Epub 2008 Oct 22. PMID:18977146 doi:10.1016/j.bmc.2008.10.041

Page seeded by OCA on Wed Feb 18 08:02:16 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zm4"
Personal tools