2chm

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{{STRUCTURE_2chm| PDB=2chm | SCENE= }}
{{STRUCTURE_2chm| PDB=2chm | SCENE= }}
===CRYSTAL STRUCTURE OF N2 SUBSTITUTED PYRAZOLO PYRIMIDINONES-A FLIPPED BINDING MODE IN PDE5===
===CRYSTAL STRUCTURE OF N2 SUBSTITUTED PYRAZOLO PYRIMIDINONES-A FLIPPED BINDING MODE IN PDE5===
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{{ABSTRACT_PUBMED_16759100}}
{{ABSTRACT_PUBMED_16759100}}
==About this Structure==
==About this Structure==
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2CHM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHM OCA].
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[[2chm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHM OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16759100</ref><references group="xtra"/>
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<ref group="xtra">PMID:016759100</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Allerton, C M.N.]]
[[Category: Allerton, C M.N.]]
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[[Category: Summerhill, N W.]]
[[Category: Summerhill, N W.]]
[[Category: Allosteric enzyme]]
[[Category: Allosteric enzyme]]
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[[Category: Alternative splicing]]
 
[[Category: Camp]]
[[Category: Camp]]
[[Category: Cgmp]]
[[Category: Cgmp]]
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[[Category: Phosphodiesterase 5]]
[[Category: Phosphodiesterase 5]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
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[[Category: Zinc]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:00:02 2009''
 

Revision as of 09:19, 6 January 2013

Template:STRUCTURE 2chm

CRYSTAL STRUCTURE OF N2 SUBSTITUTED PYRAZOLO PYRIMIDINONES-A FLIPPED BINDING MODE IN PDE5

Template:ABSTRACT PUBMED 16759100

About this Structure

2chm is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Allerton CM, Barber CG, Beaumont KC, Brown DG, Cole SM, Ellis D, Lane CA, Maw GN, Mount NM, Rawson DJ, Robinson CM, Street SD, Summerhill NW. A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability. J Med Chem. 2006 Jun 15;49(12):3581-94. PMID:16759100 doi:10.1021/jm060113e

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