1x70
From Proteopedia
(Difference between revisions)
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[[Image:1x70.png|left|200px]] | [[Image:1x70.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1x70]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X70 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Sitagliptin]] | ||
==Reference== | ==Reference== | ||
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[[Category: Beta-propeller]] | [[Category: Beta-propeller]] | ||
[[Category: Dimer]] | [[Category: Dimer]] | ||
| - | + | [[Category: Hydrolase]] | |
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Revision as of 13:14, 28 December 2010
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| 1x70, resolution 2.10Å () | |||||||||
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| Ligands: | , , , | ||||||||
| Gene: | DPP4, ADCP2, CD26 (Homo sapiens) | ||||||||
| Activity: | Dipeptidyl-peptidase IV, with EC number 3.4.14.5 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
HUMAN DIPEPTIDYL PEPTIDASE IV IN COMPLEX WITH A BETA AMINO ACID INHIBITOR
Template:ABSTRACT PUBMED 15634008
About this Structure
1x70 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kim D, Wang L, Beconi M, Eiermann GJ, Fisher MH, He H, Hickey GJ, Kowalchick JE, Leiting B, Lyons K, Marsilio F, McCann ME, Patel RA, Petrov A, Scapin G, Patel SB, Roy RS, Wu JK, Wyvratt MJ, Zhang BB, Zhu L, Thornberry NA, Weber AE. (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J Med Chem. 2005 Jan 13;48(1):141-51. PMID:15634008 doi:10.1021/jm0493156
Categories: Dipeptidyl-peptidase IV | Homo sapiens | Beconi, M. | Eiermann, G J. | Fisher, M H. | He, H. | Hickey, G J. | Kim, D. | Leiting, B. | Lyons, K. | Wang, L. | Alpha/beta | Beta-propeller | Dimer | Hydrolase
