2zhr
From Proteopedia
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===Crystal structure of BACE1 in complex with OM99-2 at pH 5.0=== | ===Crystal structure of BACE1 in complex with OM99-2 at pH 5.0=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2zhr]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZHR OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018378702</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Nukina, N.]] | [[Category: Nukina, N.]] | ||
[[Category: Shimizu, H.]] | [[Category: Shimizu, H.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
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[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Om99-2 complex]] | [[Category: Om99-2 complex]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:51:16 2009'' | ||
Revision as of 11:11, 25 July 2012
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| 2zhr, resolution 2.50Å () | |||||||||
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| Non-Standard Residues: | |||||||||
| Gene: | BACE1 (Homo sapiens) | ||||||||
| Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||||
| Related: | 2zhs, 2zht, 2zhu, 2zhv | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Crystal structure of BACE1 in complex with OM99-2 at pH 5.0
Template:ABSTRACT PUBMED 18378702
About this Structure
2zhr is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Shimizu H, Tosaki A, Kaneko K, Hisano T, Sakurai T, Nukina N. Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production. Mol Cell Biol. 2008 Jun;28(11):3663-71. Epub 2008 Mar 31. PMID:18378702 doi:10.1128/MCB.02185-07
