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2nnx
From Proteopedia
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[[Image:2nnx.png|left|200px]] | [[Image:2nnx.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_17092942}} | {{ABSTRACT_PUBMED_17092942}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147450 147450]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2nnx]] is a 4 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NNX OCA]. | |
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| + | ==See Also== | ||
| + | *[[Superoxide Dismutase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Superoxide acceptor]] | [[Category: Superoxide acceptor]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:11:06 2009'' | ||
Revision as of 23:46, 26 December 2010
Contents |
Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase
Template:ABSTRACT PUBMED 17092942
About this Structure
2nnx is a 4 chain structure of Superoxide Dismutase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang J, Caruano-Yzermans A, Rodriguez A, Scheurmann JP, Slunt HH, Cao X, Gitlin J, Hart PJ, Borchelt DR. Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability. J Biol Chem. 2007 Jan 5;282(1):345-52. Epub 2006 Nov 8. PMID:17092942 doi:10.1074/jbc.M604503200
