1jud
From Proteopedia
(New page: 200px<br /> <applet load="1jud" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jud, resolution 2.5Å" /> '''L-2-HALOACID DEHALOG...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1JUD is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas Pseudomonas]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.2 3.8.1.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JUD OCA]]. | + | 1JUD is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas Pseudomonas]]. Active as [[http://en.wikipedia.org/wiki/(S)-2-haloacid_dehalogenase (S)-2-haloacid dehalogenase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.2 3.8.1.2]]. Structure known Active Site: CAT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JUD OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of L-2-haloacid dehalogenase from Pseudomonas sp. YL. An alpha/beta hydrolase structure that is different from the alpha/beta hydrolase fold., Hisano T, Hata Y, Fujii T, Liu JQ, Kurihara T, Esaki N, Soda K, J Biol Chem. 1996 Aug 23;271(34):20322-30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8702766 8702766] | Crystal structure of L-2-haloacid dehalogenase from Pseudomonas sp. YL. An alpha/beta hydrolase structure that is different from the alpha/beta hydrolase fold., Hisano T, Hata Y, Fujii T, Liu JQ, Kurihara T, Esaki N, Soda K, J Biol Chem. 1996 Aug 23;271(34):20322-30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8702766 8702766] | ||
| + | [[Category: (S)-2-haloacid dehalogenase]] | ||
[[Category: Pseudomonas]] | [[Category: Pseudomonas]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: hydrolase]] | [[Category: hydrolase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:04:07 2007'' |
Revision as of 11:59, 30 October 2007
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L-2-HALOACID DEHALOGENASE
Overview
L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of, L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic, acids. The crystal structure of the homodimeric enzyme from Pseudomonas, sp. YL has been determined by a multiple isomorphous replacement method, and refined at 2.5 A resolution to a crystallographic R-factor of 19.5%., The subunit consists of two structurally distinct domains: the core domain, and the subdomain. The core domain has an alpha/beta structure formed by a, six-stranded parallel beta-sheet flanked by five alpha-helices. The, subdomain inserted into the core domain has a four helix bundle structure, providing the greater part of the interface for dimer formation. There is, an active site cavity between the domains. An experimentally ... [(full description)]
About this Structure
1JUD is a [Single protein] structure of sequence from [Pseudomonas]. Active as [(S)-2-haloacid dehalogenase], with EC number [3.8.1.2]. Structure known Active Site: CAT. Full crystallographic information is available from [OCA].
Reference
Crystal structure of L-2-haloacid dehalogenase from Pseudomonas sp. YL. An alpha/beta hydrolase structure that is different from the alpha/beta hydrolase fold., Hisano T, Hata Y, Fujii T, Liu JQ, Kurihara T, Esaki N, Soda K, J Biol Chem. 1996 Aug 23;271(34):20322-30. PMID:8702766
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