1xy1
From Proteopedia
(New page: 200px<br /><applet load="1xy1" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xy1, resolution 1.04Å" /> '''CRYSTAL STRUCTURE AN...) |
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| - | [[Image:1xy1.jpg|left|200px]]<br /><applet load="1xy1" size=" | + | [[Image:1xy1.jpg|left|200px]]<br /><applet load="1xy1" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1xy1, resolution 1.04Å" /> | caption="1xy1, resolution 1.04Å" /> | ||
'''CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING'''<br /> | '''CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Two crystal structures of deamino-oxytocin have been determined at better | + | Two crystal structures of deamino-oxytocin have been determined at better than 1.1A resolution from isomorphous replacement and anomalous scattering x-ray measurements. In each of two crystal forms there are two closely related conformers with disulfide bridges of different chirality, which may be important in receptor recognition and activation. |
==About this Structure== | ==About this Structure== | ||
| - | 1XY1 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with NH2 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1XY1 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XY1 OCA]. |
==Reference== | ==Reference== | ||
Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding., Wood SP, Tickle IJ, Treharne AM, Pitts JE, Mascarenhas Y, Li JY, Husain J, Cooper S, Blundell TL, Hruby VJ, et al., Science. 1986 May 2;232(4750):633-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3008332 3008332] | Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding., Wood SP, Tickle IJ, Treharne AM, Pitts JE, Mascarenhas Y, Li JY, Husain J, Cooper S, Blundell TL, Hruby VJ, et al., Science. 1986 May 2;232(4750):633-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3008332 3008332] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Blundell, T | + | [[Category: Blundell, T L.]] |
[[Category: Cooper, S.]] | [[Category: Cooper, S.]] | ||
[[Category: Husain, J.]] | [[Category: Husain, J.]] | ||
| - | [[Category: Pitts, J | + | [[Category: Pitts, J E.]] |
| - | [[Category: Tickle, I | + | [[Category: Tickle, I J.]] |
| - | [[Category: Wood, S | + | [[Category: Wood, S P.]] |
[[Category: NH2]] | [[Category: NH2]] | ||
[[Category: hormone]] | [[Category: hormone]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:59:57 2008'' |
Revision as of 13:59, 21 February 2008
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CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING
Overview
Two crystal structures of deamino-oxytocin have been determined at better than 1.1A resolution from isomorphous replacement and anomalous scattering x-ray measurements. In each of two crystal forms there are two closely related conformers with disulfide bridges of different chirality, which may be important in receptor recognition and activation.
About this Structure
1XY1 is a Protein complex structure of sequences from [1] with as ligand. Full crystallographic information is available from OCA.
Reference
Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding., Wood SP, Tickle IJ, Treharne AM, Pitts JE, Mascarenhas Y, Li JY, Husain J, Cooper S, Blundell TL, Hruby VJ, et al., Science. 1986 May 2;232(4750):633-6. PMID:3008332
Page seeded by OCA on Thu Feb 21 15:59:57 2008
Categories: Protein complex | Blundell, T L. | Cooper, S. | Husain, J. | Pitts, J E. | Tickle, I J. | Wood, S P. | NH2 | Hormone
