1pj3
From Proteopedia
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[[Image:1pj3.png|left|200px]] | [[Image:1pj3.png|left|200px]] | ||
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{{STRUCTURE_1pj3| PDB=1pj3 | SCENE= }} | {{STRUCTURE_1pj3| PDB=1pj3 | SCENE= }} | ||
===Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate.=== | ===Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate.=== | ||
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{{ABSTRACT_PUBMED_12962632}} | {{ABSTRACT_PUBMED_12962632}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Epilepsy, idopathic generalized, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=154270 154270]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1pj3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PJ3 OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012962632</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Tao, X.]] | [[Category: Tao, X.]] | ||
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[[Category: Yang, Z.]] | [[Category: Yang, Z.]] | ||
[[Category: Oxidative decarboxylase]] | [[Category: Oxidative decarboxylase]] | ||
- | + | [[Category: Oxidoreductase]] | |
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Revision as of 11:56, 19 December 2012
Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate.
Template:ABSTRACT PUBMED 12962632
About this Structure
1pj3 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Tao X, Yang Z, Tong L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure. 2003 Sep;11(9):1141-50. PMID:12962632