1pj3

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[[Image:1pj3.png|left|200px]]
[[Image:1pj3.png|left|200px]]
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{{STRUCTURE_1pj3| PDB=1pj3 | SCENE= }}
{{STRUCTURE_1pj3| PDB=1pj3 | SCENE= }}
===Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate.===
===Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate.===
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{{ABSTRACT_PUBMED_12962632}}
{{ABSTRACT_PUBMED_12962632}}
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==Disease==
 
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Known disease associated with this structure: Epilepsy, idopathic generalized, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=154270 154270]]
 
==About this Structure==
==About this Structure==
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1PJ3 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PJ3 OCA].
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[[1pj3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PJ3 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:12962632</ref><references group="xtra"/>
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<ref group="xtra">PMID:012962632</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Tao, X.]]
[[Category: Tao, X.]]
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[[Category: Yang, Z.]]
[[Category: Yang, Z.]]
[[Category: Oxidative decarboxylase]]
[[Category: Oxidative decarboxylase]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:27:41 2009''
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Revision as of 11:56, 19 December 2012

Template:STRUCTURE 1pj3

Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate.

Template:ABSTRACT PUBMED 12962632

About this Structure

1pj3 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tao X, Yang Z, Tong L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure. 2003 Sep;11(9):1141-50. PMID:12962632

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