2pjy

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===Structural basis for cooperative assembly of the TGF-beta signaling complex===
===Structural basis for cooperative assembly of the TGF-beta signaling complex===
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The line below this paragraph, {{ABSTRACT_PUBMED_18243111}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18243111 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18243111}}
==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2PJY is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJY OCA].
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2PJY is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJY OCA].
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==Reference==
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<ref group="xtra">PMID:18243111</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Receptor protein serine/threonine kinase]]
[[Category: Groppe, J.]]
[[Category: Groppe, J.]]
[[Category: Zubieta, C.]]
[[Category: Zubieta, C.]]
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[[Category: Cytokine/cytokine receptor complex]]
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[[Category: Cytokine-cytokine receptor complex]]
[[Category: Ternary complex]]
[[Category: Ternary complex]]
[[Category: Three finger toxin]]
[[Category: Three finger toxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:55:13 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 08:56:08 2010''

Revision as of 06:56, 17 March 2010

Template:STRUCTURE 2pjy

Contents

Structural basis for cooperative assembly of the TGF-beta signaling complex

Template:ABSTRACT PUBMED 18243111

Disease

Known disease associated with this structure: Arrhythmogenic right ventricular dysplasia 1 OMIM:[190230], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[190182], Esophageal cancer OMIM:[190182], Loeys-Dietz syndrome, type 1B OMIM:[190182], Loeys-Dietz syndrome, type 2B OMIM:[190182], Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]

About this Structure

2PJY is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Groppe J, Hinck CS, Samavarchi-Tehrani P, Zubieta C, Schuermann JP, Taylor AB, Schwarz PM, Wrana JL, Hinck AP. Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol Cell. 2008 Feb 1;29(2):157-68. PMID:18243111 doi:10.1016/j.molcel.2007.11.039

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