2pjy
From Proteopedia
(Difference between revisions)
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===Structural basis for cooperative assembly of the TGF-beta signaling complex=== | ===Structural basis for cooperative assembly of the TGF-beta signaling complex=== | ||
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+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_18243111}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 18243111 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_18243111}} | ||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
- | 2PJY is a 3 chains structure | + | 2PJY is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PJY OCA]. |
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+ | ==Reference== | ||
+ | <ref group="xtra">PMID:18243111</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein serine/threonine kinase]] | [[Category: Receptor protein serine/threonine kinase]] | ||
[[Category: Groppe, J.]] | [[Category: Groppe, J.]] | ||
[[Category: Zubieta, C.]] | [[Category: Zubieta, C.]] | ||
- | [[Category: Cytokine | + | [[Category: Cytokine-cytokine receptor complex]] |
[[Category: Ternary complex]] | [[Category: Ternary complex]] | ||
[[Category: Three finger toxin]] | [[Category: Three finger toxin]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 08:56:08 2010'' |
Revision as of 06:56, 17 March 2010
Contents |
Structural basis for cooperative assembly of the TGF-beta signaling complex
Template:ABSTRACT PUBMED 18243111
Disease
Known disease associated with this structure: Arrhythmogenic right ventricular dysplasia 1 OMIM:[190230], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[190182], Esophageal cancer OMIM:[190182], Loeys-Dietz syndrome, type 1B OMIM:[190182], Loeys-Dietz syndrome, type 2B OMIM:[190182], Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]
About this Structure
2PJY is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Groppe J, Hinck CS, Samavarchi-Tehrani P, Zubieta C, Schuermann JP, Taylor AB, Schwarz PM, Wrana JL, Hinck AP. Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol Cell. 2008 Feb 1;29(2):157-68. PMID:18243111 doi:10.1016/j.molcel.2007.11.039
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