3czr
From Proteopedia
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===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Arylsulfonylpiperazine Inhibitor=== | ===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Arylsulfonylpiperazine Inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3czr]] is a 2 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZR OCA]. | |
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| + | ==See Also== | ||
| + | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018511278</ref><references group="xtra"/> |
[[Category: 11-beta-hydroxysteroid dehydrogenase]] | [[Category: 11-beta-hydroxysteroid dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Nadp]] | [[Category: Nadp]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
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[[Category: Signal-anchor]] | [[Category: Signal-anchor]] | ||
[[Category: Steroid metabolism]] | [[Category: Steroid metabolism]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
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Revision as of 15:36, 25 July 2012
Contents |
Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Arylsulfonylpiperazine Inhibitor
Template:ABSTRACT PUBMED 18511278
About this Structure
3czr is a 2 chain structure of Hydroxysteroid dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sun D, Wang Z, Di Y, Jaen JC, Labelle M, Ma J, Miao S, Sudom A, Tang L, Tomooka CS, Tu H, Ursu S, Walker N, Yan X, Ye Q, Powers JP. Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). Bioorg Med Chem Lett. 2008 Jun 15;18(12):3513-6. Epub 2008 May 10. PMID:18511278 doi:http://dx.doi.org/10.1016/j.bmcl.2008.05.025
Categories: 11-beta-hydroxysteroid dehydrogenase | Homo sapiens | Sudom, A. | Walker, N P. | Wang, Z. | 11beta | Dehydrogenase | Endoplasmic reticulum | Glycoprotein | Hydroxysteroid | Lipid metabolism | Membrane | Microsome | Nadp | Oxidoreductase | Signal-anchor | Steroid metabolism | Transmembrane
