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2hh4

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[[Image:2hh4.png|left|200px]]
[[Image:2hh4.png|left|200px]]
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{{STRUCTURE_2hh4| PDB=2hh4 | SCENE= }}
{{STRUCTURE_2hh4| PDB=2hh4 | SCENE= }}
===NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures===
===NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures===
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{{ABSTRACT_PUBMED_16762918}}
{{ABSTRACT_PUBMED_16762918}}
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==Disease==
 
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Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], Hyperproinsulinemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]], MODY, one form OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]]
 
==About this Structure==
==About this Structure==
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2HH4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HH4 OCA].
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[[2hh4]] is a 2 chain structure of [[Molecular Playground/Insulin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HH4 OCA].
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==See Also==
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*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16762918</ref><references group="xtra"/>
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<ref group="xtra">PMID:016762918</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hu, S Q.]]
[[Category: Hu, S Q.]]
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[[Category: Weiss, M A.]]
[[Category: Weiss, M A.]]
[[Category: Hormone]]
[[Category: Hormone]]
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[[Category: Hormone-growth factor complex]]
[[Category: Human insulin]]
[[Category: Human insulin]]
[[Category: Mutant]]
[[Category: Mutant]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:09:06 2009''
 

Revision as of 15:41, 25 July 2012

Template:STRUCTURE 2hh4

Contents

NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Template:ABSTRACT PUBMED 16762918

About this Structure

2hh4 is a 2 chain structure of Molecular Playground/Insulin with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  • Hua QX, Nakagawa S, Hu SQ, Jia W, Wang S, Weiss MA. Toward the active conformation of insulin: stereospecific modulation of a structural switch in the B chain. J Biol Chem. 2006 Aug 25;281(34):24900-9. Epub 2006 Jun 8. PMID:16762918 doi:http://dx.doi.org/10.1074/jbc.M602691200

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