2jiv

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===CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION IN COMPEX WITH HKI-272===
===CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION IN COMPEX WITH HKI-272===
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{{ABSTRACT_PUBMED_18227510}}
==About this Structure==
==About this Structure==
2JIV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JIV OCA].
2JIV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JIV OCA].
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==Reference==
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<ref group="xtra">PMID:18227510</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Eck, M J.]]
[[Category: Eck, M J.]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:23:10 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 11:19:43 2009''

Revision as of 09:19, 22 March 2009

Image:2jiv.png

Template:STRUCTURE 2jiv

CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION IN COMPEX WITH HKI-272

Template:ABSTRACT PUBMED 18227510

About this Structure

2JIV is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2070-5. Epub 2008 Jan 28. PMID:18227510

Page seeded by OCA on Sun Mar 22 11:19:43 2009

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