This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1nys
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1nys.png|left|200px]] | [[Image:1nys.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1nys", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1nys| PDB=1nys | SCENE= }} | {{STRUCTURE_1nys| PDB=1nys | SCENE= }} | ||
===Crystal Structure of Activin A Bound to the ECD of ActRIIB P41=== | ===Crystal Structure of Activin A Bound to the ECD of ActRIIB P41=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_12660162}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 12660162 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_12660162}} | {{ABSTRACT_PUBMED_12660162}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1nys]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYS OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012660162</ref><ref group="xtra">PMID:017295905</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| Line 32: | Line 20: | ||
[[Category: Actriib]] | [[Category: Actriib]] | ||
[[Category: Extracellular domain]] | [[Category: Extracellular domain]] | ||
| + | [[Category: Membrane protein-hormone-growth factor complex]] | ||
[[Category: Tgf beta]] | [[Category: Tgf beta]] | ||
[[Category: Type ii]] | [[Category: Type ii]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:26:10 2009'' | ||
Revision as of 20:59, 5 December 2012
Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
Template:ABSTRACT PUBMED 12660162
About this Structure
1nys is a 4 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Thompson TB, Woodruff TK, Jardetzky TS. Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions. EMBO J. 2003 Apr 1;22(7):1555-66. PMID:12660162 doi:10.1093/emboj/cdg156
- Weber D, Kotzsch A, Nickel J, Harth S, Seher A, Mueller U, Sebald W, Mueller TD. A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. BMC Struct Biol. 2007 Feb 12;7:6. PMID:17295905 doi:10.1186/1472-6807-7-6
