2p8s
From Proteopedia
(Difference between revisions)
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[[Image:2p8s.png|left|200px]] | [[Image:2p8s.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[2p8s]] is a 2 chain structure of [[Dipeptidyl peptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8S OCA]. | |
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+ | ==See Also== | ||
+ | *[[Dipeptidyl peptidase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Beta-propeller]] | [[Category: Beta-propeller]] | ||
[[Category: Dimer]] | [[Category: Dimer]] | ||
+ | [[Category: Hydrolase]] | ||
[[Category: Structure-based design]] | [[Category: Structure-based design]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:53:49 2009'' |
Revision as of 11:50, 3 January 2011
Contents |
Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor
Template:ABSTRACT PUBMED 17433672
About this Structure
2p8s is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE. Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3384-7. Epub 2007 Apr 2. PMID:17433672 doi:10.1016/j.bmcl.2007.03.095