3b2r
From Proteopedia
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===Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil=== | ===Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3b2r]] is a 2 chain structure of [[Phosphodiesterase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2R OCA]. | |
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| + | ==See Also== | ||
| + | *[[Phosphodiesterase|Phosphodiesterase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017959709</ref><references group="xtra"/> |
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | [[Category: 3',5'-cyclic-GMP phosphodiesterase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Sharron, H F.]] | [[Category: Sharron, H F.]] | ||
[[Category: Allosteric enzyme]] | [[Category: Allosteric enzyme]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cgmp phosphodiesterase]] | [[Category: Cgmp phosphodiesterase]] | ||
[[Category: Cgmp-binding]] | [[Category: Cgmp-binding]] | ||
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[[Category: Pde5-inhibitor potency]] | [[Category: Pde5-inhibitor potency]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Sildenafil]] | [[Category: Sildenafil]] | ||
[[Category: Vardenafil]] | [[Category: Vardenafil]] | ||
| - | [[Category: Zinc]] | ||
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Revision as of 20:15, 25 July 2012
Contents |
Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
Template:ABSTRACT PUBMED 17959709
About this Structure
3b2r is a 2 chain structure of Phosphodiesterase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang H, Ye M, Robinson H, Francis SH, Ke H. Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol Pharmacol. 2008 Jan;73(1):104-10. Epub 2007 Oct 24. PMID:17959709 doi:10.1124/mol.107.040212
Categories: 3',5'-cyclic-GMP phosphodiesterase | Homo sapiens | Hengming, K. | Howard, R. | Huanchen, W. | Mengchun, Y. | Sharron, H F. | Allosteric enzyme | Cgmp phosphodiesterase | Cgmp-binding | Hydrolase | Levitratm. | Magnesium | Metal-binding | Nucleotide-binding | Pde5-inhibitor potency | Phosphorylation | Sildenafil | Vardenafil
