2j38
From Proteopedia
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[[Image:2j38.png|left|200px]] | [[Image:2j38.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
- | + | [[2j38]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J38 OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:16982192</ref><references group="xtra"/> | + | <ref group="xtra">PMID:16982192</ref><ref group="xtra">PMID:17338508</ref><references group="xtra"/> |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:42:18 2009'' |
Revision as of 20:09, 14 March 2011
CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
Template:ABSTRACT PUBMED 16982192
About this Structure
2j38 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Senger S, Convery MA, Chan C, Watson NS. Arylsulfonamides: a study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5731-5. Epub 2006 Sep 18. PMID:16982192 doi:http://dx.doi.org/10.1016/j.bmcl.2006.08.092
- Chan C, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chung CW, Convery MA, Hamblin JN, Johnstone L, Kelly HA, Kleanthous S, Patikis A, Patel C, Pateman AJ, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Whitworth C, Young RJ, Zhou P. Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl }sulfonamides. J Med Chem. 2007 Apr 5;50(7):1546-57. Epub 2007 Mar 6. PMID:17338508 doi:http://dx.doi.org/10.1021/jm060870c
Categories: Coagulation factor Xa | Homo sapiens | Chan, C. | Convery, M A. | Senger, S. | Watson, N S. | Blood coagulation | Calcium | Complex | Egf-like domain | Gamma- carboxyglutamic acid | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Polymorphism | Protease | Serine protease | Zymogen