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1pv8
(Difference between revisions)
Categories: Homo sapiens | Porphobilinogen synthase | Breinig, S. | Fairman, R. | Jaffe, E K. | Kervinen, J. | Stith, L. | Wasson, A S. | Wlodawer, A. | Zdanov, A. | Lyase | Reaction intermediate | Tetrapyrrole biosynthesis
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{{STRUCTURE_1pv8| PDB=1pv8 | SCENE= }} | {{STRUCTURE_1pv8| PDB=1pv8 | SCENE= }} | ||
| - | ===Crystal structure of a low activity F12L mutant of human | + | ===Crystal structure of a low activity F12L mutant of human porphobilinogen synthase=== |
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==About this Structure== | ==About this Structure== | ||
| - | 1PV8 is a 2 chains structure | + | 1PV8 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PV8 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Wlodawer, A.]] | [[Category: Wlodawer, A.]] | ||
[[Category: Zdanov, A.]] | [[Category: Zdanov, A.]] | ||
| + | [[Category: Lyase]] | ||
[[Category: Porphobilinogen synthase]] | [[Category: Porphobilinogen synthase]] | ||
[[Category: Reaction intermediate]] | [[Category: Reaction intermediate]] | ||
[[Category: Tetrapyrrole biosynthesis]] | [[Category: Tetrapyrrole biosynthesis]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:24:50 2010'' |
Revision as of 04:20, 2 June 2010
Contents |
Crystal structure of a low activity F12L mutant of human porphobilinogen synthase
Template:ABSTRACT PUBMED 12897770
Disease
Known disease associated with this structure: Porphyria, acute hepatic OMIM:[125270], Lead poisoning, susceptibility to OMIM:[125270]
About this Structure
1PV8 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Breinig S, Kervinen J, Stith L, Wasson AS, Fairman R, Wlodawer A, Zdanov A, Jaffe EK. Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase. Nat Struct Biol. 2003 Sep;10(9):757-63. Epub 2003 Aug 3. PMID:12897770 doi:10.1038/nsb963
Page seeded by OCA on Wed Jun 2 08:24:50 2010