This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3d7v
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3d7v.png|left|200px]] | [[Image:3d7v.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3d7v", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3d7v| PDB=3d7v | SCENE= }} | {{STRUCTURE_3d7v| PDB=3d7v | SCENE= }} | ||
===Crystal structure of Mcl-1 in complex with an Mcl-1 selective BH3 ligand=== | ===Crystal structure of Mcl-1 in complex with an Mcl-1 selective BH3 ligand=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18209102}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18209102 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18209102}} | {{ABSTRACT_PUBMED_18209102}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3d7v]] is a 2 chain structure of [[Bcl-2]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus,_homo_sapiens Mus musculus, homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D7V OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Bcl-2|Bcl-2]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018209102</ref><references group="xtra"/> |
[[Category: Mus musculus, homo sapiens]] | [[Category: Mus musculus, homo sapiens]] | ||
[[Category: Colman, P M.]] | [[Category: Colman, P M.]] | ||
| Line 29: | Line 20: | ||
[[Category: Fairlie, W D.]] | [[Category: Fairlie, W D.]] | ||
[[Category: Lee, E F.]] | [[Category: Lee, E F.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Amphipathic helix]] | [[Category: Amphipathic helix]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Developmental protein]] | [[Category: Developmental protein]] | ||
[[Category: Differentiation]] | [[Category: Differentiation]] | ||
| Line 40: | Line 29: | ||
[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | [[Category: Ubl conjugation]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:18:57 2009'' | ||
Revision as of 22:52, 25 July 2012
Contents |
Crystal structure of Mcl-1 in complex with an Mcl-1 selective BH3 ligand
Template:ABSTRACT PUBMED 18209102
About this Structure
3d7v is a 2 chain structure of Bcl-2 with sequence from Mus musculus, homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lee EF, Czabotar PE, van Delft MF, Michalak EM, Boyle MJ, Willis SN, Puthalakath H, Bouillet P, Colman PM, Huang DC, Fairlie WD. A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation. J Cell Biol. 2008 Jan 28;180(2):341-55. Epub 2008 Jan 21. PMID:18209102 doi:10.1083/jcb.200708096
